{"id":758,"date":"2016-04-03T20:22:08","date_gmt":"2016-04-03T19:22:08","guid":{"rendered":"https:\/\/www.principelle.com\/?page_id=758"},"modified":"2026-06-10T14:00:21","modified_gmt":"2026-06-10T14:00:21","slug":"principelle-if","status":"publish","type":"page","link":"https:\/\/principelle.com\/?page_id=758","title":{"rendered":"Principelle IF"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"758\" class=\"elementor elementor-758\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5e27321f0 e-con-full e-flex wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-equal-height-no e-con e-parent\" data-id=\"5e27321f0\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e9b909f e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-equal-height-no e-con e-parent\" data-id=\"e9b909f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-5505acae e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-equal-height-no elementor-invisible e-con e-child\" data-id=\"5505acae\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInLeft&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5583c471 elementor-widget elementor-widget-image\" data-id=\"5583c471\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"960\" height=\"960\" src=\"https:\/\/principelle.com\/wp-content\/uploads\/2026\/06\/PRNCP-160729-8849-copy.jpeg\" class=\"attachment-large size-large wp-image-2249\" alt=\"\" srcset=\"https:\/\/principelle.com\/wp-content\/uploads\/2026\/06\/PRNCP-160729-8849-copy.jpeg 960w, https:\/\/principelle.com\/wp-content\/uploads\/2026\/06\/PRNCP-160729-8849-copy-300x300.jpeg 300w, https:\/\/principelle.com\/wp-content\/uploads\/2026\/06\/PRNCP-160729-8849-copy-150x150.jpeg 150w, https:\/\/principelle.com\/wp-content\/uploads\/2026\/06\/PRNCP-160729-8849-copy-768x768.jpeg 768w\" sizes=\"(max-width: 960px) 100vw, 960px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-17cb7191 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-equal-height-no elementor-invisible e-con e-child\" data-id=\"17cb7191\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInRight&quot;,&quot;animation_delay&quot;:100}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7aae14b3 elementor-widget elementor-widget-heading\" data-id=\"7aae14b3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Principelle IF<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1b1159ec elementor-widget elementor-widget-text-editor\" data-id=\"1b1159ec\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<h3>Advanced wound care designed to support healing.<\/h3>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9c7f61d elementor-widget elementor-widget-text-editor\" data-id=\"9c7f61d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<h5>Chronic wounds are stuck in a non-resolved cycle arising from imbalances in the levels and activity associated with moisture, proteins, ions and bacteria.<br \/>Contamination and infection further complicate healing. Some wounds (deep wounds, cavities) only allow for the application of liquid solutions. Appropriate natural components intervene to achieve protease and pH modulation. Altering<br \/>the woundbed conditions and environment guides chronic wounds back to appropriate stages of healing.<\/h5>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3921566 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-equal-height-no e-con e-parent\" data-id=\"3921566\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-5e19bca1 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-equal-height-no elementor-invisible e-con e-child\" data-id=\"5e19bca1\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInLeft&quot;,&quot;animation_delay&quot;:200}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-764155d6 elementor-widget elementor-widget-heading\" data-id=\"764155d6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Powered by nature. Guided by science.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2e2e53e2 elementor-widget elementor-widget-text-editor\" data-id=\"2e2e53e2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<h5>Principelle IF formulation contains no synthetic components. Minerals, trace elements and oxides are carried by a specially selected dark buckwheat honey.<br \/>The process of mixing components is done to an unusual high standard. The anti-bacterial properties of the medical grade honey is well acknowledged. Low moisture content, free acids, and a rich source of phenolic compounds lend the product effective natural qualities against a wide range of pathogens, including MRSA.<\/h5><h5>IF Ointment can be used for acute and chronic wounds. It is particularly suitable for decubitus (grade 3-4 Wagner), cavity and tunneling wounds. It may be used on moderately-exuding, lightly exuding and dry wounds. With a suitable secondary dressing it can also be used on heavily exuding wounds. Depending on the wound type it may be covered by traditional dressings, or absorbing<br \/>dressing such as Principelle Matrix.<\/h5>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-3d205e95 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-equal-height-no elementor-invisible e-con e-child\" data-id=\"3d205e95\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInRight&quot;,&quot;animation_delay&quot;:300}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-67977497 elementor-widget elementor-widget-image\" data-id=\"67977497\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"683\" height=\"1024\" src=\"https:\/\/principelle.com\/wp-content\/uploads\/2026\/05\/annie-spratt-hX_hf2lPpUU-unsplash-683x1024.jpg\" class=\"attachment-large size-large wp-image-2214\" alt=\"\" srcset=\"https:\/\/principelle.com\/wp-content\/uploads\/2026\/05\/annie-spratt-hX_hf2lPpUU-unsplash-683x1024.jpg 683w, https:\/\/principelle.com\/wp-content\/uploads\/2026\/05\/annie-spratt-hX_hf2lPpUU-unsplash-200x300.jpg 200w, https:\/\/principelle.com\/wp-content\/uploads\/2026\/05\/annie-spratt-hX_hf2lPpUU-unsplash-768x1151.jpg 768w, https:\/\/principelle.com\/wp-content\/uploads\/2026\/05\/annie-spratt-hX_hf2lPpUU-unsplash-1025x1536.jpg 1025w\" sizes=\"(max-width: 683px) 100vw, 683px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2820a85f e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-equal-height-no e-con e-parent\" data-id=\"2820a85f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-4a64b5fa e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-equal-height-no elementor-invisible e-con e-child\" data-id=\"4a64b5fa\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInLeft&quot;,&quot;animation_delay&quot;:400}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-60ecf8f1 elementor-widget elementor-widget-image\" data-id=\"60ecf8f1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"792\" height=\"1024\" src=\"https:\/\/principelle.com\/wp-content\/uploads\/2026\/06\/armennano-ladybug-4089546-792x1024.jpg\" class=\"attachment-large size-large wp-image-2252\" alt=\"\" srcset=\"https:\/\/principelle.com\/wp-content\/uploads\/2026\/06\/armennano-ladybug-4089546-792x1024.jpg 792w, https:\/\/principelle.com\/wp-content\/uploads\/2026\/06\/armennano-ladybug-4089546-232x300.jpg 232w, https:\/\/principelle.com\/wp-content\/uploads\/2026\/06\/armennano-ladybug-4089546-768x993.jpg 768w, https:\/\/principelle.com\/wp-content\/uploads\/2026\/06\/armennano-ladybug-4089546-1188x1536.jpg 1188w, https:\/\/principelle.com\/wp-content\/uploads\/2026\/06\/armennano-ladybug-4089546-1584x2048.jpg 1584w, https:\/\/principelle.com\/wp-content\/uploads\/2026\/06\/armennano-ladybug-4089546-scaled.jpg 1980w\" sizes=\"(max-width: 792px) 100vw, 792px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-598cbebd e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-equal-height-no elementor-invisible e-con e-child\" data-id=\"598cbebd\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;slideInRight&quot;,&quot;animation_delay&quot;:500}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-36273140 elementor-widget elementor-widget-heading\" data-id=\"36273140\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Key Features<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a4665ca elementor-widget elementor-widget-spacer\" data-id=\"a4665ca\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-620e0d78 wpr-feature-list-left wpr-feature-list-square wpr-feature-list-line-yes elementor-widget elementor-widget-wpr-feature-list\" data-id=\"620e0d78\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"wpr-feature-list.default\">\n\t\t\t\t\t<div class=\"wpr-feature-list-wrap\"><ul class=\"wpr-feature-list\"><li class=\"wpr-feature-list-item elementor-repeater-item-de85061\"><div class=\"wpr-feature-list-icon-wrap\"><span class=\"wpr-feature-list-line\"><\/span><div class=\"wpr-feature-list-icon-inner-wrap\"><\/div><\/div><div class=\"wpr-feature-list-content-wrap\"><h2 class=\"wpr-feature-list-title\"><a class=\"wpr-feature-list-url\" target=\"_blank\" rel=\"nofollow\">Clinically informed design<\/a><\/h2><p class=\"wpr-feature-list-description\">Developed with a strong focus on practical clinical application and ease of use.<\/p><\/div><\/li><li class=\"wpr-feature-list-item elementor-repeater-item-f6e3624\"><div class=\"wpr-feature-list-icon-wrap\"><span class=\"wpr-feature-list-line\"><\/span><div class=\"wpr-feature-list-icon-inner-wrap\"><\/div><\/div><div class=\"wpr-feature-list-content-wrap\"><h2 class=\"wpr-feature-list-title\"><a class=\"wpr-feature-list-url\" target=\"_blank\" rel=\"nofollow\">Supports wound healing<\/a><\/h2><p class=\"wpr-feature-list-description\">Helps create conditions that support the body's natural healing mechanisms.\n<\/p><\/div><\/li><li class=\"wpr-feature-list-item elementor-repeater-item-22171bd\"><div class=\"wpr-feature-list-icon-wrap\"><span class=\"wpr-feature-list-line\"><\/span><div class=\"wpr-feature-list-icon-inner-wrap\"><\/div><\/div><div class=\"wpr-feature-list-content-wrap\"><h2 class=\"wpr-feature-list-title\"><a class=\"wpr-feature-list-url\" target=\"_blank\" rel=\"nofollow\">Protective environment<\/a><\/h2><p class=\"wpr-feature-list-description\">Contributes to maintaining a balanced wound environment that promotes recovery.<\/p><\/div><\/li><li class=\"wpr-feature-list-item elementor-repeater-item-4a05209\"><div class=\"wpr-feature-list-icon-wrap\"><span class=\"wpr-feature-list-line\"><\/span><div class=\"wpr-feature-list-icon-inner-wrap\"><\/div><\/div><div class=\"wpr-feature-list-content-wrap\"><h2 class=\"wpr-feature-list-title\"><a class=\"wpr-feature-list-url\" target=\"_blank\" rel=\"nofollow\">Professional application<\/a><\/h2><p class=\"wpr-feature-list-description\">Suitable for use within professional wound care protocols and treatment plans.<\/p><\/div><\/li><\/ul><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-92ffd04 e-flex e-con-boxed wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no wpr-equal-height-no e-con e-parent\" data-id=\"92ffd04\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t\t\n<hr class=\"e-divider-base\" data-interaction-id=\"fa7e0c9\"   \/>\n\t\t\t\t<div class=\"elementor-element elementor-element-0c68f4c elementor-widget elementor-widget-text-editor\" data-id=\"0c68f4c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<h2>Product files<\/h2><ul><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2014\/02\/Product-Brochure-Principelle-IF.pdf\">Product brochure (English)<\/a>, also available in <a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/HR-121211-PP-Flyer-IF-Dutch-NL.pdf\">Dutch<\/a>, <a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/HR-121211-PP-Flyer-IF-French.pdf\">French<\/a>, <a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/HR-121211-PP-Flyer-IF-Italian.pdf\">Italian<\/a> and <a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/HR-121211-PP-Flyer-IF-Spanish.pdf\">Spanish<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2018\/10\/1602-09.05-Principelle-IF-dressing-IFU-HR.pdf\">Instructions for Use Principelle IF Dressings<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2018\/10\/1608-01.02-HR-IFU-PP-IF-Tube-10_20g.pdf\">Instructions for Use Principelle IF Ointment<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2017\/10\/Principelle-Wound-Classification-Model-ENG.pdf\">Wound classification model<\/a><\/li><\/ul><h2>Case reports<\/h2><ul><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/06-11-2013-Case-report-Principelle-IF.pdf\">Case Report Principelle IF<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/26-06-2014-Case-report-Principelle-IF-ointment-Principelle-Matrix-and-MelMax.pdf\">Case Report Principelle IF ointment, Principelle Matrix and MelMax<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/23-04-2014-Case-Report-Principelle-IF-MelMax-and-Principelle-Matrix.pdf\">Case Report Principelle IF, MelMax and Principelle Matrix<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/23-04-2014-Case-Report-Principelle-IF-and-Principelle-Matrix.pdf\">Case Report Principelle IF and Principelle Matrix<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/12-11-2013-Case-report-MelMax-Principelle-IF-Veterinary.pdf\">Case Report MelMax &amp; Principelle IF (Veterinary use)<\/a><\/li><\/ul><h2>Relevant literature<\/h2><ul><li><a href=\"https:\/\/principelle.com\/wordpress\/wp-content\/uploads\/2021\/07\/Angioi-2021-The-Rediscovery-of-Honey-for-Skin-Repair_Applied-Sciences.pdf\">The Rediscovery of Honey for Skin Repair: Recent Advances in Mechanisms for Honey-Mediated Wound Healing and Scaffolded Application Techniques &#8211; Angioi 2021<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/Research-Report-Antibacterial-Activity-PPIF15.pdf\">Research Report Antibacterial Activity of Principelle IF ointment<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/Mechanism-of-honey-bacteriostatic-action-against-MRSA-Brudzynski-2013.pdf\">Mechanism of honey bacteriostatic action against MRSA &#8211; Brudzynski 2013<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/Honey-exposure-stimulates-wound-repair-of-human-dermal-fibroblasts-Ranzato-2013.pdf\">Honey exposure stimulates wound repair of human dermal fibroblasts &#8211; Ranzato 2013<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/Powerful-bacterial-killing-by-buckwheat-honeys-Brudzynski-2012.pdf\">Powerful bacterial killing by buckwheat honeys &#8211; Brudzynski 2012<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/The-evidence-and-the-rationale-for-the-use-of-honey-as-a-wound-dressing-Peter-Molan-2011.pdf\">The evidence and the rationale for the use of honey as a wound dressing &#8211; Molan 2011<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/Are-all-wound-products-created-equally-The-re-emergence-of-natural-honey-Al-Lenjawi-2015.pdf\">Are all wound products created equally? The re-emergence of natural honey &#8211; Al-Lenjawi 2015<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/An-in-vitro-examination-of-the-antioxidant-and-anti-inflammatory-properties-of-buckwheat-honey-Van-den-Berg-2008.pdf\">An in vitro examination of the antioxidant and anti-inflammatory properties of buckwheat honey &#8211; Van den Berg 2008<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/The-significance-of-surface-pH-in-chronic-wounds-2007-1.pdf\">The significance of surface pH in chronic wounds &#8211; Gethin 2007<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/The-Evidence-Supporting-the-use-of-honey-as-a-wound-dressing-Peter-Molan-2006.pdf\">The Evidence Supporting the use of honey as a wound dressing &#8211; Molan 2006<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/A-clinical-prospective-study-assessing-the-efficacy-of-a-fenolic-rich-honey-and-PHI-5-dressing-in-therapy-resistant-and-colonized-burn-defects-Hoeksema-2005.pdf\">A clinical prospective study assessing the efficacy of a fenolic rich honey and PHI-5 dressing in therapy resistant and colonized burn defects &#8211; Hoeksema 2005<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/Clinical-usage-of-honey-as-a-wound-dressing-an-update-Molan-2004.pdf\">Clinical usage of honey as a wound dressing, an update &#8211; Molan 2004<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/The-Effect-of-Dilution-on-the-Rate-of-Hydrogen-Peroxide-Production-in-Honey-and-Its-Implications-for-Wound-Healing-Bang-2003.pdf\">The Effect of Dilution on the Rate of Hydrogen Peroxide Production in Honey and Its Implications for Wound Healing &#8211; Bang 2003<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/Potential-of-Honey-in-Treatment-of-Wounds-and-Burns-Peter-Molan-2001.pdf\">Potential of Honey in Treatment of Wounds and Burns &#8211; Molan 2001<\/a><\/li><li><a href=\"https:\/\/www.principelle.com\/wordpress\/wp-content\/uploads\/2016\/04\/Methylglyoxal\u2014A-Potential-Risk-Factor-of-Manuka-Honey-in-Healing-of-Diabetic-Ulcers-Majtan-2009.pdf\">Methylglyoxal &#8211; A Potential Risk Factor of Manuka Honey in Healing of Diabetic Ulcers &#8211; Majtan 2009<\/a><\/li><\/ul><h2>\u00a0<\/h2><h2>Product pictures, packshots &amp; artwork<\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Principelle IF Advanced wound care designed to support healing. Chronic wounds are stuck in a non-resolved cycle arising from imbalances in the levels and activity associated with moisture, proteins, ions and bacteria.Contamination and infection further complicate healing. Some wounds (deep wounds, cavities) only allow for the application of liquid solutions. Appropriate natural components intervene to achieve protease and pH modulation. Alteringthe woundbed conditions and environment guides chronic wounds back to appropriate stages of healing. Powered by nature. Guided by science. Principelle IF formulation contains no synthetic components. Minerals, trace elements and oxides are carried by a specially selected dark buckwheat honey.The process of mixing components is done to an unusual high standard. The anti-bacterial properties of the medical grade honey is well acknowledged. Low moisture content, free acids, and a rich source of phenolic compounds lend the product effective natural qualities against a wide range of pathogens, including MRSA. IF Ointment can be used for acute and chronic wounds. It is particularly suitable for decubitus (grade 3-4 Wagner), cavity and tunneling wounds. It may be used on moderately-exuding, lightly exuding and dry wounds. With a suitable secondary dressing it can also be used on heavily exuding wounds. Depending on the wound type it may be covered by traditional dressings, or absorbingdressing such as Principelle Matrix. Key Features Clinically informed design Developed with a strong focus on practical clinical application and ease of use. Supports wound healing Helps create conditions that support the body&#8217;s natural healing mechanisms. Protective environment Contributes to maintaining a balanced wound environment that promotes recovery. Professional application Suitable for use within professional wound care protocols and treatment plans. Product files Product brochure (English), also available in Dutch, French, Italian and Spanish Instructions for Use Principelle IF Dressings Instructions for Use Principelle IF Ointment Wound classification model Case reports Case Report Principelle IF Case Report Principelle IF ointment, Principelle Matrix and MelMax Case Report Principelle IF, MelMax and Principelle Matrix Case Report Principelle IF and Principelle Matrix Case Report MelMax &amp; Principelle IF (Veterinary use) Relevant literature The Rediscovery of Honey for Skin Repair: Recent Advances in Mechanisms for Honey-Mediated Wound Healing and Scaffolded Application Techniques &#8211; Angioi 2021 Research Report Antibacterial Activity of Principelle IF ointment Mechanism of honey bacteriostatic action against MRSA &#8211; Brudzynski 2013 Honey exposure stimulates wound repair of human dermal fibroblasts &#8211; Ranzato 2013 Powerful bacterial killing by buckwheat honeys &#8211; Brudzynski 2012 The evidence and the rationale for the use of honey as a wound dressing &#8211; Molan 2011 Are all wound products created equally? The re-emergence of natural honey &#8211; Al-Lenjawi 2015 An in vitro examination of the antioxidant and anti-inflammatory properties of buckwheat honey &#8211; Van den Berg 2008 The significance of surface pH in chronic wounds &#8211; Gethin 2007 The Evidence Supporting the use of honey as a wound dressing &#8211; Molan 2006 A clinical prospective study assessing the efficacy of a fenolic rich honey and PHI-5 dressing in therapy resistant and colonized burn defects &#8211; Hoeksema 2005 Clinical usage of honey as a wound dressing, an update &#8211; Molan 2004 The Effect of Dilution on the Rate of Hydrogen Peroxide Production in Honey and Its Implications for Wound Healing &#8211; Bang 2003 Potential of Honey in Treatment of Wounds and Burns &#8211; Molan 2001 Methylglyoxal &#8211; A Potential Risk Factor of Manuka Honey in Healing of Diabetic Ulcers &#8211; Majtan 2009 \u00a0 Product pictures, packshots &amp; artwork<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":748,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-758","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/principelle.com\/index.php?rest_route=\/wp\/v2\/pages\/758","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/principelle.com\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/principelle.com\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/principelle.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/principelle.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=758"}],"version-history":[{"count":18,"href":"https:\/\/principelle.com\/index.php?rest_route=\/wp\/v2\/pages\/758\/revisions"}],"predecessor-version":[{"id":2368,"href":"https:\/\/principelle.com\/index.php?rest_route=\/wp\/v2\/pages\/758\/revisions\/2368"}],"up":[{"embeddable":true,"href":"https:\/\/principelle.com\/index.php?rest_route=\/wp\/v2\/pages\/748"}],"wp:attachment":[{"href":"https:\/\/principelle.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=758"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}